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healthcare-in-europe.com
Putting β-glucan testing into everyday practice for fungal infections

Invasive fungal infections are notoriously hard to catch early, and even harder to rule out with confidence. At the Parasitology-Mycology Laboratory of CHU Bordeaux, Consultant Physician Dr Frédéric Gabriel has spent years refining how his lab uses β-D-glucan (BDG) testing to sharpen that judgement call – including with the Wako β-glucan test. In this interview, he explains what the guidelines say, what actually happens at the bench, and where he sees the test heading next.

Phys.org
Uncovering how Cryptococcus shifts from silent infection to killer fungus

For most healthy people, Cryptococcus is an unnoticed infection. The immune system walls it off in the lungs and keeps it dormant for life. But in patients undergoing cancer chemotherapy, recovering from an organ transplant, living with HIV or taking newer immunosuppressing drugs for autoimmune disease, the fungus can reactivate, spread to the brain and cause meningitis.

Medical Xpress
Traditional prostate cancer risk factors do not predict hormone therapy benefit, study finds

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer—such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles—after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation.

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